The Revolting Revenge of the Radioactive Robo-Boxers is an installment in the Captain Underpants series. The narrative focuses on a new, ridiculous, and highly threatening villain: a pair of Radioactive Robo-Boxers created to exact revenge on the titular superhero. The plot sees George Beard and Harold Hutchins assisting the incompetent Captain Underpants in combating the giant mechanical threat, leading to predictably chaotic and hilarious results involving giant fighting robots and silly, slapstick humor.